The presented work’s topic is „position-related automatic adjustment of graphical user interfaces on mobile devices“. After an extensive literature review of related work, a concept for the design of the GUI was developed, based on a small user survey. Five adjustment categories were derived on the basis of which design rules could be established. Special emphasis was put on the filtering options and layout of an overview of an application, and how additional GUI elements can be turned on and off. There have also been included various feedback techniques to make the user aware of options of interaction, and to inform him of any system changes. Adjustments can be both implicitly and explicitly triggered. The use of multimodal interaction techniques was also considered. Furthermore, a functional prototype in the from of an Android Application was developed. It’s implementation was based on the previously developed design rules and nearly all previously determined adjustment categories where implemented as an example.